Graph of daily activity patterns

Physical Activity

Physical activity is healthy for the aging brain and may reduce the risk of Alzheimer's disease. We have several studies using body worn activity monitors to measure sedentary behavior, physical activity, and sleep in older adults with and without Alzheimer’s Disease.

Example Publications


Ghosal, R., Varma, V. R., Volfson, D., Hillel, I., Urbanek, J., Hausdorff, J. M., Watts, A., & Zipunnikov, V. (2021). Distributional data analysis via quantile functions and its application to modelling digital biomarkers of gait in Alzheimer’s Disease. Biostatistics, kxab041 doi:10.1093/biostatistics/kxab041.

Hicks, H., Laffer, A., Meyer, K., & Watts, A. (2021). Estimates of Physical Activity in Older Adults using the ActiGraph Low Frequency Extension Filter. Journal for the Measurement of Physical Behaviour. doi:10.1123/jmpb.2020-0034.

Varma, V., Ghosal, R., Volfson, D., Weiss, J., Urbanek, J., Hausdorff, J., Zipunnikov, V., & Watts, A. (2021). Continuous gait monitoring discriminates community dwelling mild AD from cognitively normal controls. Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 7(1) doi:10.1002/trc2.12131.

Salazar-Villanea, M., Chacón-Araya, Y., Watts, A., Vidoni, E. D., Billinger, S. A, Johnson, D. K., & Moncada-Jiménez, J. (2021). Aerobic fitness and neurocognitive performance in older adults from Kansas and Costa Rica. International Journal of Sport Psychology, 52, 248-265. doi: 10.7352/IJSP.2021.52.248.

Vidoni, E. D., Morris, J. K., Watts, A., Perry, M., Clutton, J., Van Sciver, A., Kamat, A., Mahnken, J., Hunt, S. L., Townley, R., Honea, R., Shaw, A. R., Johnson, D. K., Vacek, J., Burns, J. M., (2021). Effect of aerobic exercise on amyloid accumulation in preclinical Alzheimer’s: A 1-year randomized controlled trial. PLoS One, doi:10.1101/2020.08.03.20167684.

Kaufman, C. S., Honea, R. A., Pleen, J., Lepping, R. J., Watts, A., Morris, J. K., Billinger, S. A., Burns, J. M., & Vidoni, E. D. (2021). Aerobic exercise improves hippocampal blood flow for hypertensive apolipoprotein ε4 carriers. Journal of Cerebral Blood Flow and Metabolism. doi: 10.1177/0271678X21990342. PMID: 33509035.

Chacón-Araya, Y., Briceño-Torres, J. M., Peralta-Brenes, M., Hernández-Gamboa, R., Johnson, D. K., Watts, A., Vidoni, E. D., Billinger, S. A., Salazar-Villanea, M., & Moncada-Jiménez, J. (2020). Predicting exertion from metabolic, physiological and cognitive variables in older adults. Pensamiento Psicológico, 18(2), 1-27. doi:/10.11144/Javerianacali.PPSI18-2.pemp

Bevan, A., Vidoni, E., & Watts, A. (2020). Rate of perceived exertion and cardiorespiratory fitness in older adults with and without Alzheimer’s disease. International Journal of Exercise Science, 13(3), 18-35. PMID: 32148626 PMCID: PMC7039494

Watts, A., Garnier-Villarreal, M., Gardiner, P. (2018). Sitting time in older adults with and without Alzheimer’s disease. Journal for the Measurement of Physical Behaviour. DOI:10.1123/jmpb.2018-0002.

Farina, N., Hughes, L. J., Watts, A., & Lowry, R. G. (2019). Use of physical activity questionnaires in people with dementia: A scoping review. Journal of Aging and Physical Activity. doi: 10.1123/japa.2018-0031

Khou, C., Rendzia, B., & Watts, A. (2018). Evaluation of waist-worn actigraphy monitors for the assessment of sleep in older adults with and without Alzheimer's disease. Journal of Rehabilitation and Assistive Technologies Engineering. DOI:10.1177/2055668318777989.

Watts, A., Mortby, M., & Burns, J. (2018). Depressive symptoms as a barrier to engagement in physical activity in older adults with and without Alzheimer’s disease. PLOSONE 13(12): e0208581. https://doi.org/10.1371/journal.pone.0208581.

Watts, A., Andrews, S., & Anstey, K. (2018). Sex differences in the impact of BDNF genotype on the longitudinal relationship between physical activity and cognitive performance. Gerontology. DOI: 10.1159/000486369.

Varma, V. R., & Watts, A. (2017). Daily physical activity patterns during the early stage of Alzheimer's disease. Journal of Alzheimer's Disease. doi: 10.3233/JAD-160582

Watts, A., Walters, R., Hoffman, L., & Templin, J. (2016). Intra-individual variability of physical activity in older adults with and without mild Alzheimer’s disease. PLoS One. http://dx.doi.org/10.1371/journal.pone.0153898

Vidoni, E., Watts, A., Burns, J. M., et al. (2016). Feasibility of a memory clinic-based physical activity prescription program. Journal of Alzheimer’s Disease. 53(1), 161-170 doi:10.3233/JAD-160158

Rhyner, K. T., & Watts, A. (2016). Exercise and depressive symptoms in older adults: A systematic meta-analytic review. Journal of Aging and Physical Activity. doi:10.1123/japa.2015-0146

Watts, A., Vidoni, E., Loskutova, N., Johnson, D. K., & Burns, J. (2013). Measuring physical activity in older adults with and without Alzheimer’s disease. Clinical Gerontologist, 36(4), 1-20.